The official journal of The Sri Lanka Veterinary Association
PLASMA PROTEIN CONCENTRATION AND ALANINE AMINOTRANSFERASE ACTIVITY IN RESPONSE TO DIFFERENT REMEDIAL THERAPIES IN MALASSEZIA DERMATITIS IN COMPANION DOGS
Journal - Sri Lanka Veterinary Journal (volume: 62)
Volume - 62
Year - 2015
Page Number - 7
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Short Communication

S.L.Vet.J. 2015, 62(A): 7-10

PLASMA PROTEIN CONCENTRATION AND ALANINE AMINOTRANSFERASE ACTIVITY IN RESPONSE TO DIFFERENT REMEDIAL THERAPIES IN MALASSEZIA DERMATITIS IN COMPANION DOGS

Rucha Borkar M.V.Sc, Kabita Roy Ph.D, P.C. Shukla Ph.D, Amita Tiwari Ph.D and I.C. Datta Ph.D

Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry,
The Nanaji Deshmukh Veterinary Science University, South Civil Lines, Jabalpur, MP- 482 001, India

SUMMARY: A study was conducted on client-owned dog patients brought for treatment in the Out Patient Department (Medicine), Teaching Veterinary Clinical Complex, Veterinary College, Jabalpur, M.P., India. Of the total 240 dogs with clinical signs of dermatitis, Malassezia dermatitis was confirmed in 60 cases by microscopic examination of the modified Wright stained impression smear and fungal culture on Sabouraud's dextrose agar plate. Synthetic antifungal, ketoconazole and flucoconazole were offered in two different doses (pulse therapy, 4 cycles). Herbal Neem (Azadarichta indica, Linn.) leaf extract powder at two graded dose levels was given with food daily for 4 weeks. Broad spectrum antibacterial, cephalexin for 5 days daily, and herbal hepatoprotective sylimarin, were offered orally daily in all six combination regimens. Herbal Neem seed oil (NSO) was applied topically on the skin lesions daily, and shampoo (2% miconazole plus 2% chlorhexidine), followed by body wash once a week was recommended. In all six treatment groups, the circulatory protein profile remained virtually unaltered. However, statistically significant (P <0.05) changes were recorded in Alanine aminotransferase with biomedical implications.

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How to cite:

Rucha Borkar, Kabita Roy, P.C. Shukla, Amita Tiwari and I.C. Datta,(2015). Plasma protein concentration and alanine aminotransferase activity in response to different remedial therapies in Malassezia dermatitis in companion dogs. Sri Lanka Veterinary Journal. 62(A), pp.7–6.

Keywords: Malassezia dermatitis, Alanine aminotransferase, ALT, Dog, Plasma protein,Shampoo, Chlorhexidine, Miconazole, Neem, Azadarichta indica